Meldonium-MIC (Mildronate) is an anti-ischemic metabolic modulator with strong links to improved physical performance. It can increase in endurance performance of athletes, improved rehabilitation after exercise, protection against stress, and enhanced activations of central nervous system (CNS) functions. Neurological clinics have also had positive results using meldonium for the treatment of brain circulation disorders. Some people use meldonium as a nootropic to improve brain function.

Meldonium is available in two sizes:

        The maximum suggested daily dosage is 2000mg. In athletes, this is often taken as two split dosages of 500mg-1000mg taken 30-60 minutes prior to exercise. As a nootropic, it is often taken first thing in the morning. Dosages for heart problems or brain circulation disorders will vary.

        As yet, there is a lack of clinical testing for side effects. Due to the mechanisms of action of meldonium, side effects you may expect to experience include dyspepsia, agitation, tachycardia, hypotension and pruritus.

        Do not use if performing in a sports environment where you will be tested for drug us. Meldonium is now listed as a banned substance by WADA (the World Anti-Doping Agency).

        There is a lack safety data available regarding use by pregnant or breastfeeding women or in children. Do not use meldonium if you belong to these groups.

        Meldonium is excreted renally. Your doctor should be aware if you have any kidney or liver problems.

        Some hypotensive drugs can have their antianginal effect increased by meldonium.